Frequently Asked Questions

Ans. Maori Miracle is a new and unique arthritis formula backed by a large body of peer reviewed research spanning the past 30 years. Therapeutx, (the manufacturers of Maori Miracle), took a different approach by going to the experts first rather than developing a formula and then trying to get the experts to endorse it. Maori Miracle goes beyond glucosamine, chondroitin, MSM and the many herbal remedies currently on the market. Yes those other formulas are safe and offer some albeit limited benefit; on a 1 to 10 scale I would place those other formulas at about a 3 and Maori Miracle at a 10. Maori Miracle is a far more significant arthritis formula than anything currently on the market. Maori Miracle was designed to clean up the synovial fluid, rebuild and protect cartilage, lubricate joints, ligaments & tendons and acts as a powerful natural anti-inflammatory; Maori Miracle treats the underlying cause of the disease rather than just the symptoms.

Ans. As the answer to this question can be extensive depending on how much technical depth the reader wishes to go; please refer to the answer to #1 above and review the “Practitioner’s Guide” on this website. Additionally there are links which provide more in-depth reading on each ingredient in Maori Miracle. Keep in mind that Maori Miracle offers great prophylactic values as a preventative as well as a treatment remedy for both osteo and rheumatoid arthritis.

Ans. This is the most common asked question and certainly a valid one. There is no single hard and fast answer as there are many forms of arthritis and each in varying degrees of severity. For examples moderate arthritis in the fingers will see relief sooner than severe arthritis of the spine. Rheumatoid arthritis is more difficult and often responds at a slower rate. If I may generalize from our own surveys and research, the short answer seems to be 21 days – keeping in mind that one should double up on the dosage (i.e. 3 caps in the morning and 3 in the evening) for the first 1 -2 bottles as a loading dose.

Ans. There are two ingredients in Maori Miracle (GlycoMarine (Biolane) & Myristin) which have beneficial properties in the treatment of rheumatoid arthritis (RA). Although the exact mode of action of Myristin is not clear we know it acts like an immunomodulator. RA being an auto-immune disorder thus responds well to Myristin. As to GlycoMarine (Biolane) please see the response provided by John Croft to Q2 in the additional FAQ’s under the heading “John Croft Answers the Most Frequently Asked Questions About GlycoMarine™ (Biolane)” below. Also RA is accompanied by soft tissue inflammation which is relieved in part by the salicin in white willow bark extract.

Ans. Yes, you can, but please refer to the answer to question # 23 below.

Ans. You may take Maori Miracle with meals or on an empty stomach, ideally in the morning.

Ans. No, you take all 3 caps at once. We needed to give a specific amount to make the dose effective and that would have been a capsule too large for most to swallow so we broke it down to 3 smaller capsules, but take them all at once. Keep in mind that if you have moderate to severe arthritis, it is recommended that you double up on the dosage for the first 1 -2 bottles as a loading dose, and in that case you would take 3 caps in the morning and another 3 in the afternoon or evening.

Ans. This is another really good question. Therapeutx researched and examined several kinds and sources of green lipped mussel extracts. Most of the extracts proved to be no better than placebo while a couple had some limited benefit. GlycoMarine (Biolane) however stood out and showed significant benefit and proved to be effective in so many treatment areas for arthritis. GlycoMarine (Biolane) is manufactured using a unique proprietary stabilized extraction method that retains the necessary active ingredients. Also GlycoMarine (Biolane) is extracted from one and only one particular species of green lipped mussel, Perna canaliculus, which is only found in New Zealand waters. For more on GlycoMarine (Biolane) see the additional FAQ’s answered by John Croft below.

Ans. Our research told us that collagen would be a necessary ingredient in the formula – but what kind of collagen and from what source. Collagen can be hydrolyzed or unhydrolyzed and can be sourced from bovine, porcine, avian and shark sources – it was a challenge to discover what type and what source would prove to be the most effective for treating arthritic disorders. Again the short answer here is that unhydrolyzed is the most effective type and avian (chicken sternum) is the most effective source. And further the collagen extracted from the sternums of young chickens was the most effective. We chose Kolla2 because it is unhydrolyzed and extracted from young chicken sternum cartilage. Kolla2 also has the highest concentration of hyaluronic acid of any collagen.

Ans. Myristin (Cetyl myristoleate) is the original Cetyl myristoleate as discovered by Harry Diehl in 1964, since then there have been several attempts to duplicate this material but none has been able to match Myristin’s superior effectiveness for treating arthritis and other musculoskeletal ailments. Again, in the same way GlycoMarine and Kolla2 brought their unique properties to the Maori Miracle formula through their patented manufacturing process, Myristin brought its unique properties to the Maori Miracle formula through its unique process. Myristin is patented in the treatment of both osteo and rheumatoid arthritis. Myristin helps regulate the immune system, instead of just treating the symptoms of pain and inflammation… the cause being your immune system that attacks your joints. Once your immune system is supported, the attack on your joints stops and the pain and inflammation is significantly relieved. Myristin provides relief from pain & swelling and the return of mobility. No other Cetyl myristoleate was shown to be as effective as Myristin.

Ans. The short answer is yes, Maori Miracle is very safe even at high doses. Maori Miracle is gastro protective (protects your stomach lining) and it is chondroprotective (protects your joints and cartilage). There are no known contraindications or interactions between Maori Miracle and any other medication. Our focus in developing Maori Miracle was “Safety & Efficacy – the formula had to work effectively and be completely safe. We’re happy to say we’ve accomplished both those goals. If you are on blood thinners please refer to question 23 and if you are pregnant or lactating always speak with your personal health care practitioner prior to taking any new medications. Also Maori Miracle is not recommended for those with gout or shellfish allergies.

Ans. Yes and for cats. You can open a few capsules and sprinkle the powder on their food.

Ans. If you are pregnant, you should consult with your physician prior to taking any new medication. Maori Miracle, despite its extreme safety also follows this rule.

Ans. Maori Miracle is available at health food stores and better pharmacies across Canada. You may also visit our online store.

Ans. If you have gout or shellfish allergies we do not recommend you take Maori Miracle.

Ans. It is recommended that you double up on the dose for the first 1 – 2 bottles of Maori Miracle (i.e. take 3 caps in the morning and another 3 caps in the evening). If you stop taking Maori Miracle the pain and swelling may return in a week or so, depending on the severity of your arthritis. Keep in mind that what took years to develop (as is the case in osteo arthritis where the articular cartilage is worn away), will not be healed overnight. I had terrible arthritis in my shoulders from a lifetime of swimming and I’ve been taking Maori Miracle for 2 years, I’m fine now, have been for some time and I’m back swimming. For the past 4 months I’ve gone to 3 caps every second day as a maintenance dose and it seems to be working fine.

Ans. Hydrolyzed collagen protein is pre-digested outside the body breaking down the amino acid chain by a process of adding synthesized enzymes and chemicals. It is then spray-dried into powder using very high temperatures. When chicken sternal cartilage collagen type II protein is exposed to high temperature, as is the case in the manufacture of hydrolyzed collagen, the delicate hyaluronic acid and sugar aminos molecules become less effective. Laboratory testing has shown that the severe heat and acid steps necessary in hydrolysis can destroy the vital carbohydrate nutrients (mucopolysaccharides) including hyaluronic acid, glucosamine, and chondroitin. Furthermore, the hydrolysis process washes most of the lipid molecules away. UnHydrolyzed Kolla2® as found in Maori Miracle® uses a low temperature process that ensures biological activity for maximum results. Advanced exclusive and patented technology extracts the Kolla2® from young chicken sternum cartilage yielding healthy active cells. No other collagen supplement does this. Kolla2® unhydrolyzed chicken sternum cartilage collagen type II as found in Maori Miracle® preserves a low-molecular weight structure as well as more of the important mucopolysaccharides. Kolla2® unhydrolyzed collagen type II leaves the long chains of amino acids intact, allowing the body’s own superior natural enzymes to recognize the precise genetic code in the healthy active molecules for maximum assimilation. This provides chicken sternal collagen type II as a building block for the body to heal itself, especially in cases of osteoarthritis.

Ans. We colour coded our capsules in accordance with the Codex recommendations to insure that Maori Miralce will not be mistaken for any other medication. This involved printing our name on each capsule and colour coding each capsule. The green colour is chlorophyll.

Ans. Maori Miracle is a far more significant arthritic remedy than any Glucosamine/Chondroitin/MSM or herbal formula but to answer your question, those other products do have some efficacy and they are safe so if you can afford to keep taking them, by all means do. I was a continuous user of Glucosamine, Chondroitin and MSM (all in one formula) but I never realized real significant benefit until I began taking Maori Miracle and now that’s all I take.

Ans. No, and it is always good business to keep your doctor informed about what additional medications you are taking. Feel free to bring this website to your doctor’s attention and especially the Practitioner’s Guide, which is listed on this website.

Ans. Sad to say, there is as yet no known cure for arthritis; it seems to be an on-going degenerative process that is a part of life and aging, although it has been know to strike young persons as well. If you feel “cured” I would still take Maori Miracle at least every second day as a maintenance dose to keep you feeling “cured.”

Ans. Thank you for the interesting question, we turned our minds to this very question some time ago and I’m happy to report that Capsugel (our supplier of gelatin caps) has set the standard as recognized by Health Canada to ensure there is no possibility of any contamination of any kind including BSE, in their gelatin capsules. We have been provided with their research and test results for every batch of caps we purchase; I won’t bore you with those as they are lengthy and technical. Maori Miracle caps are completely safe.

Ans. This is another very important question and from a legal stand point I will have to be cautious in my answer. We originally had lipase in the formula to help with the absorption of the other ingredients. We discovered that the lipase broke down the GlycoMarine(Biolane) long-chain fatty acids in the stomach and rendered it ineffective. We remove lipase from the formula (although we see it is an ingredient is several competitive arthritis formulas) and we substituted white willow bark extract with 15% natural salicin content. Keep in mind if you want a natural source of salicin and the product is boasting white willow at greater than 15% natural salicin, be cautious, it’s probably spiked with synthetic salicin. White willow bark extract doesn’t impair blood coagulation to the same extent as aspirin. Nonetheless, it seems reasonable to suppose that if it is used in high doses willow could still cause the side effects associated with aspirin. At standard doses (120mg – 240mg/day, willow may interact adversely with anti-coagulants and other anti-inflammatory drugs such as methotrexate, metoclopramide, phenytoin, probenecid, spironolactone, and valproate. Although the concern with blood thinners relates to standard doses of willow bark offering between 120mg and 240mg of salicin; a daily dose of Maori Miracle® (3 capsules) contains only 22 ½ mg of salicin. Therapeutx™ purposely incorporated a smaller amount of white willow bark extract into Maori Miracle® because many arthritic suffers are middle aged or elderly and are on blood thinners; that being the case, we set the willow bark extract amount in each capsule lower, so as to provide some benefit without adversely affecting those on blood thinning/anti-coagulant medication. If you are taking blood thinners, please discuss this information to your doctor or health care provider.

More FAQ’s on GlycoMarine answered by John Croft

John Croft Answers the Most Frequently Asked Questions About GlycoMarine™(Biolane)

Q1. How did you discover that the New Zealand Green-Lipped Mussel (Perna canaliculus) had properties which could be used to treat arthritic diseases?
A1. The discovery was made when this mussel was involved in a research programme which looked at marine mollusks (shellfish) to see if any of them contained a possible treatment for cancer. The New Zealand Green-Lipped Mussel (GLM) was included in this programme because it is unique and is only found in New Zealand’s waters.
Nothing was found in the mussel that would help in the treatment of cancer, but the trials indicated that the GLM demonstrated significant anti-inflammatory activity, and anti-inflammatory drugs are used to treat arthritis. Thus, it was thought that GLM might provide a valuable, natural anti-arthritic treatment for this very serious and debilitating disease. Following many years of dedicated research, an extract from the New Zealand Green Lipped Mussel – GlycoMarine™(Biolane) – has proven to be a highly successful treatment, with the added bonus of not exhibiting the classic adverse side effects associated with non-steroidal anti-inflammatory drugs (NSAIDs).

Q2. Arthritis has many forms and is a very debilitating and painful disease. How can the GlycoMarine(Biolane), which is a natural product, successfully treat such a serious condition?
A2. GlycoMarine(Biolane) has been shown in laboratory and clinical trials, treating both human and animal subjects, to be very effective in treating both the rheumatoid and osteo forms of arthritis. How it does this is an interesting story (involving the use of a few medical and scientific terms, which I will try to explain clearly) that suggests the untapped power of nature (and marine life in particular) to provide remedies for many ailments. The difficult part is finding these remedies amongst the multitude of life forms present in the seas!
GlycoMarine(Biolane) has two distinct anti-inflammatory activities naturally present. The principal anti-inflammatory activity is due to a carbohydrate complex, which has the ability to inhibit the emigration of neutrophils from blood vessels. What this means in everyday terms is that soldier cells (neutrophils) are inhibited from attacking our own cells when an inflammatory stimulus is present. This is an oversimplified explanation of neutrophil action, but hopefully, explains why the inhibition of this activity helps reduce inflammation. This same mechanism is used by some anti-inflammatory drugs.
The second anti-inflammatory activity is due to the effect of the natural content of long chain fatty acids on cyclo-oxygenase and 5-lipoxygenase activities. These compounds are enzymes, which the body uses to biosynthesise compounds called prostaglandins and leukotrienes. Unfortunately, some of these compounds are pro-inflammatory and it is therefore advantageous to inhibit their biosynthesis. Anti-inflammatory drugs such as aspirin, indomethacin and phenylbutazone perform this function effectively, but unfortunately, they also inhibit the production of prostaglandins which are needed for the protection of the stomach lining, for helping kidney function and for some blood characteristics. GlycoMarine(Biolane) has the very desirable and most important benefit of inhibiting the damaging prostaglandins whilst not influencing the necessary ones.
Another valuable feature of the product is that it has been found to have natural gastroprotective properties. This means that, not only does it not damage the delicate stomach lining, it actually provides a protective function for it. Thus, the product is able to relieve the inflammatory symptoms associated with arthritic diseases whilst protecting the stomach from the damaging effect of some painkillers, should a person find it necessary to be taking these at the same time.

Q3. You mentioned earlier that GlycoMarine(Biolane) is effective in treating osteoarthritis as well as the rheumatoid form of arthritis. Osteoarthritis has a different cause, and is a very different form of the disease, so can you explain how the product can function for both disease states?
A3. This question puzzled us for some time. We were well aware of the product’s success in treating osteoarthritis, but could not offer an adequate explanation for this success. However, the discovery of the chondroprotective activity of glucosamines and chondroitin sulfates led to the answer to our puzzle. GlycoMarine(Biolane) has a natural content of glycosaminoglycans, which is the name for a group of polysaccharides that includes chondroitin sulfate amongst a few others such as dermatan sulfate, hyaluronic acid, etc. These glycosaminoglycans (which use glucosamine molecules as the raw material for their building blocks) are used by the body for the biosynthesis of compounds called proteoglycans. The proteoglycans have a very strong affinity for water molecules in the joints, to which they bind, and form very large, slippery, space-filling molecules. The function of these large combination molecules is to act as shock absorbers and also lubricants in the joints.
Therefore, we have in GlycoMarine(Biolane) an anti-inflammatory activity, which is necessary to relieve the inflammatory component of osteoarthritis coupled with chondroprotective activity which relieves the physical problem of degenerative bone condition.
There is one further point worthy of mention here, which relates to the increased rate of cartilage degeneration in the joints in arthritic disease and also in advanced age. In young people, and those not affected by arthritis, the rate of cartilage degeneration in the joints is equaled by that of regeneration. In the older person and in arthritic disease states, this balance is upset – leading to a reduction in the padding and lubrication of the joints. Certain cytokine induced enzyme activity is known to accelerate the breakdown of the cartilage process and the inhibition of this enzymic activity is thus very desirable. GlycoMarine has been shown in laboratory studies to inhibit cytokine activity, which would lead to the production of cells responsible for this process.

Q4. You mentioned that GlycoMarine(Biolane) is an extract of the GLM. There are several products on the market which boast GLM content, are these all the same extract with the same properties as GlycoMarine(Biolane)?
A4. No, unfortunately there are several “imitation” products which do not have the beneficial properties I have described, for reasons which I will explain. This is a very important question, because people could be spending their money and hoping for relief by way of one of these products, which has no therapeutic value whatsoever! Unfortunately, the customer is not able to tell by the appearance, smell or even the nutritional analysis whether the product is the genuine extract or simply freeze-dried (lyophilised) whole mussel meats ground into a powder. The only way the customer can be sure that they are getting the genuine product is by requesting it by the brand name, GlycoMarine(Biolane).
The reason that these imitation products (which are essentially just freeze dried whole mussel powder) do not perform the functions I have described for GlycoMarine(Biolane), is that the anti-inflammatory activity of the mussel decreases at a rapid rate when the mussel dies. Additionally, if the extract is not stabilized during the extraction process it becomes nearly worthless. Thus, because mussel powders (as opposed to mussel extract powder) are made from frozen mussel meat, and in some cases, even from cooked mussel meat, the activity has been lost or destroyed. This fact does not show up in a nutritional analysis, but has to be established by a special bio-assay which has been specifically developed for proving that production batches of GlycoMarine(Biolane) have an acceptable level of activity.
There is one other mussel product which is currently being marketed which is an extract. However, it contains only the lipid (oils and fats) fraction of the mussel, which have been solvent extracted, mixed with soybean oil, and presented in soft gelatin capsule form. Whilst this product will have some of the activity which I have described for GlycoMarine(Biolane), it has only one of the active fractions which are present in GlycoMarine(Biolane), and therefore, is much less effective than the complete extract. I feel very strongly, that people suffering painful conditions such as arthritis, should not be misled into paying for products which will only lead to false hope and eventual disappointment; this is why I am happy to answer this question in such detail.

Q5. Your answer to my last question indicates clearly that you are very much against the selling of unproven or copycat products, where the marketer’s interest lies in huge profit margins rather than product efficacy. How can you satisfy people that GlycoMarine(Biolane) has been proven to benefit sufferers of arthritis? For example, has the product been subjected to proper, and independent, clinical trials?
A5. One of the reasons that I have been able to give the information in response to the earlier question with such confidence, is the fact that the product has been subjected to a number of randomized, double blind clinical trials involving both human and animal subjects. These trials have taken place in hospitals and research centres in several countries including, the USA, United Kingdom, France, Japan, and New Zealand. Further, the results of the clinical studies have confirmed the evidence received in numerous, unsolicited, anecdotal reports from people all over the world. Many of these reports have come from countries where the product is not on the market, but has been sent there by friends and relatives in other countries who have already had experience with it. By the way, a summary of all the references to these studies, most of which have been published in reputable, peer-reviewed journals, is available to anyone who wishes to confirm the validity of my statements.
To generalize both the anecdotal and controlled clinical study results, they indicate a success rate of about 70% for rheumatoid arthritis and 40% for the osteo form in human subjects. It is only fair to point out that these success rates are not better than can be achieved with regular drug therapy. However, the big advantage of the GlycoMarine(Biolane) treatment is that none of the classical adverse side effects of drug therapy will be experienced. Also, the product can be taken continuously on a long-term basis (I have personal experience with my mother who has taken GlycoMarine(Biolane) for 18 years) with no ill effects.
The benefit for animals (in particular dogs, since they have been the subject of the double blind animal studies) is even higher than that for humans. This may well be due to the fact that animals do not suffer quite the same psychological problems as humans, and therefore, have a lower incidence of unrelated stress factors competing with the treatment.
The level of success described by human subjects (success being a matter of degree) has been surprising. It has ranged from those who have just been able to open a jar or hold a pen again, through professional surgeons who have been able to resume operating practices, musicians who have resumed playing piano at concerts, to wheelchair bound subjects who have been able to resume a more normal mobility. Because of the beneficial influence noted by athletes (subsequently demonstrated in a double blind clinical trial on athletes) some football teams now issue the product to the team as routine, to minimises joint or connective tissue damage and to reduce injury time away from the field!

Q6. You have mentioned long term, continual use of GlycoMarine(Biolane). Is it necessary to take GlycoMarine(Biolane) forever?
A6. Not necessarily. Some people find that once they are experiencing a satisfactory level of relief, they can stop taking the product altogether until another flare up occurs. However, the majority of people prefer to gradually reduce the daily usage, by trial and error, until they establish the minimum daily maintenance requirement, usually one or two 500 mg capsules per day. There are, of course, some cases where it seems to be necessary to continue the full dosage all the time, but these would certainly be the rare cases.
I suspect that in many instances it is a fear of the symptoms recurring (after being free of them) that makes people reluctant to cease taking any capsules at all. Since taking them on a continual basis will not do any harm, this is quite an acceptable practice. It is also possible that there is a prophylactic benefit in relation to the inhibition of degenerative joint disease.

Q7. What is the recommended daily usage level for GlycoMarine(Biolane)?
A7. The normal level is based on about 1 gramme per day for the average adult. This equates to 2-3 capsules each day (depending on the dosage used by different brands) but there is no danger in doubling this level if desired. There have been occasions where doubling the level has achieved results which were not apparent at the recommended level, but this has not been a general finding.

Q8. Are you claiming that GlycoMarine(Biolane) has no side effects?
A8. Certainly not! In fact I do not believe that there is anything which has pharmacological activity which does not have some side effects. The question is the nature and level of side effects that might be experienced.
The side effects, which might be experienced by people using GlycoMarine(Biolane), are based on clinical trial reports, plus those reported by customers during the 30 years of worldwide usage. There are no serious adverse side effects associated with use of GlycoMarine(Biolane). However, because the product is a shellfish derivative, it may create an allergic reaction in people susceptible to shellfish allergy. If a person wishes to try the product, but suspects that they may be allergic to shellfish, they can just take one capsule per day for a few days, and if no allergy reaction occurs, they can then gradually increase up to three capsules daily. If a person does experience an allergic reaction, they should stop using the product and the symptoms will disappear. A reduction of allergy symptoms can be accelerated by the use of a suitable anti-histamine prescribed by a healthcare practitioner.
In a few cases, there has been a temporary exacerbation of arthritic symptoms shortly after commencing use. This condition has only lasted for a few days, and has almost always preceded excellent results. Obviously, if one is currently using conventional drug therapies, such as non-steroidal anti-inflammatories, it is imperative that any reduction in the consumption of these drugs takes place gradually. An individualized weaning programme should be implemented.
Some people have experienced mild indigestion and flatulence, but the likelihood of these can be minimized by making sure that the product is consumed at the start of a meal. On a positive note, there is a beneficial side effect which has been reported frequently by humans and is very noticeable in animals, namely, a significant enhancement of vitality, often described as ‘a feeling of well being’. This could, of course, be simply due to the effect of relief from pain coupled with increased freedom of movement.
Incidentally, I should advise that even though GlycoMarine is derived from a widely consumed food, the product has been subjected to the standard, international tests for toxicity as well as teratogenicity, to ensure that it is perfectly safe to consume at many times the recommended usage level without causing toxic effects or adversely influencing a developing fetus in a pregnant woman.

Q9. Is GlycoMarine(Biolane) safe to take together with other medications?
A9. There have been no reports of any contra-indications when GlycoMarine(Biolane) has been taken together with other anti-inflammatory products, whether these have been drugs or natural preparations. It is unlikely that GlycoMarine(Biolane) would contra-indicate with other pharmaceuticals due to its basic food status. However, it would be preferable for it not to be used if a person was using monoamine oxidase inhibitory drugs (anti-depressants which are not generally used). Also, it is important to note that GlycoMarine(Biolane) should not be used to treat gouty arthritis. The reason for this is that an excess of uric acid, which precipitates in the joints, causes gout. In common with cheese and wine, shellfish contains a significant level of purine nitrogen, which would act as a precursor for the biosynthesis of uric acid!

Q10. You have referred to the fact that GlycoMarine(Biolane) is beneficial for treating animals with arthritis. Do many animals suffer from arthritis?
A10. Yes, most animals suffer arthritic complaints at some stage in their lives. This tends to be degenerative joint disease in most cases, and unfortunately, the modern lifestyle has made arthritis almost inevitable for big dogs such as Labradors and German Shepherds as they reach middle to old age. Generally, it is a combination of lack of adequate physical exercise, coupled with too much food, which leads to degenerative joint disease in dogs. It is speculated that factors such as restricted movement or lack of incentive for extensive movement is what contributes to arthritis in both zoo animals and some farm animals. Domestic cats also suffer from this disorder but, probably because they tend to remain relatively agile in old age compared to the other species mentioned, the incidence in cats is lower.
GlycoMarine(Biolane) has been clinically trialed in both cats and dogs, with particularly successful results. However, the bulk of the evidence for the beneficial activities of GlycoMarine(Biolane) in animals has come from anecdotal reports from delighted owners. Reports of such effects have not been limited to owners of dogs and cats, however. In particular, racehorse trainers have reported significantly reduced ‘off track’ periods caused by inflammatory problems in their horses, followed by significantly enhanced performance when back racing. The veterinary surgeon at Auckland Zoo reported success in treating an elephant, a camel and a giraffe, all of which had developed arthritic problems. A veterinary surgeon in South Africa reported to me personally that he had successfully treated a parrot, which had been unable to grasp its perch prior to receiving the product!
These are just a few examples of the range of subjects which have responded favourably to treatment with GlycoMarine(Biolane). The importance of this evidence for me is that it removes the suggestion of a placebo effect being responsible for the results. This is a common suggestion, which is made when human subjects describe good results. I firmly believe that the combination of this evidence, together with independent clinical trials in humans and in animals, is sufficient to prove the value of this natural marine product as a safe and effective treatment for one of the world’s most debilitating diseases.

John E. Croft is a best selling author, lecturer and internationally recognized speaker. As a marine scientist and research consultant based in Auckland, New Zealand, his life work has been researching the nutritional and therapeutic properties of substances derived from the oceans.

Additional Information on GlycoMarine(Biolane)

What does GlycoMarine(Biolane) do?
GlycoMarine(Biolane) is a natural anti-inflammatory and gastroprotective compound, providing major benefits to those suffering from arthritis. As non-steroidal anti-inflammatory drugs (NSAIDs) frequently cause stomach upset, the gastroprotective qualities of GlycoMarine(Biolane) help mitigate the adverse effects of NSAIDs. Additionally, GlycoMarine(Biolane) has a natural content of glycosaminoglycans, including small naturally occurring amounts of chondroitin sulphate and glucosamine, providing chondroprotective activity – acting as both a shock absorber and lubricant to the joints.

How does GlycoMarine(Biolane) work?
GlycoMarine(Biolane) does not work like an aspirin in providing immediate relief, but begins to provide demonstrable relief as its activity builds up in the body over a period of four to six weeks. Therefore, people suffering from arthritis, who are currently taking NSAIDs, have found it beneficial to continue their normal medication regimen until GlycoMarine(Biolane) has taken hold, at which point, they should be able to gradually discontinue their use of NSAIDs without discomfort.

The product is extensively used for the treatment of rheumatoid and osteo forms of arthritic disorders in human and animal subjects. It is classed as a nutraceutical and has the backing of 30 years of peer-reviewed research to support its pharmacological activity. The main reason for its extensive use is that it is an effective natural anti-inflammatory with chondroprotective and selective cyclo-oxygenase ( COX-2 ) inhibitory properties able to be used on a long term basis without the complication of significant adverse side effects.

Pharmacological Functions:

  1. Anti-inflammatory – Inhibition of a number of pro-inflammatory neutrophil functions including, neutrophil emigration, catabolic cytokines and mediation of T-lymphocyte activity. These functions are a response to the carbohydrate component of the extract.
  2. Anti-inflammatory – Inhibition of the cyclo-oxygenase and 5-lipoxygenase enzymic cascade with COX-2 selectivity. These functions are a response to the lipid component of the extract.
  3. Gastroprotective – Protection of the stomach from the ulcerogenic effects of non steroidal anti-inflammatory drugs. This activity is a response to the lipid component of the extract.
  4. Chondroprotective – Inhibition of catabolic degradation of articular cartilage and enhancement of lubrication and buffering in the arthritic joint. This activity is a response to the amino acid and glycosaminoglycan content of the extract.
  5. Pain relief – Due to the inhibition of pain sensitising prostaglandins produced in the cyclo-oxygenase cascade a degree of pain relief is effected.

Clinical evaluations:
The product has been subjected to a number of randomised double blind and also non blinded clinical trials in both human and animal ( dogs ) subjects. The results of these have varied due to protocol suitability but have demonstrated the effectiveness of the product in rheumatoid and osteo arthritis in humans and degenerative joint disease in dogs. These trials are referenced and abstracted in the attached review.

GlycoMarine(Biolane) has been subjected to toxicity and teratogenic studies to pharmaceutical protocols and has been shown to be non toxic and not teratogenic. In addition the cultivation, harvesting and processing of the mussels used to produce the product are conducted to government approved and strictly monitored procedures. These comply with the regulatory standards of the USDA and US National Shellfish Sanitation Programme (NSSP).

Comparison with other competitive products:
The primary competition will be that of the glucosamine/chondroitin sulphate based products. However, GlycoMarine(Biolane) is superior to these products because it is multifunctional, has significantly greater anti-inflammatory activity and also performs the same chondroprotective functions as these products. Some competition may come from imitatory mussel powders. The certified anti-inflammatory activity of each batch of GlycoMarine(Biolane) will differentiate the product from these. Non steroidal anti-inflammatory drugs (NSAIDs). The relative efficacy of the product combined with its lack of significant adverse side effects and natural origin provides a strong competitive comparison.

About GlycoMarine™(Biolane)
Fact: Backed by 25 Years of Independent Laboratory Research, GlycoMarine™(Biolane) is the Only Proven Bioactive New Zealand Green Lipped Mussel Extract.
Fact: 50,000,000 Americans suffer from arthritis pain. 82% of them could get relief from a single nutriceutical.
All Natural Arthritis Relief
GlycoMarine™(Biolane) assists in relieving the pain and discomfort caused by worn and damaged joint surfaces. It is arguably one of the best-researched natural anti-inflammatory compounds that have ever entered the natural remedy market.
For over 25 years., a large body of independent laboratory and clinical research was focused on GlycoMarine™(Biolane); this research was aimed at determining both the compound’s efficacy and mode of action.
GlycoMarine™(Biolane) is a proprietary marine glycogen complex, extracted from the New Zealand green lipped mussel. The mussels are harvested exclusively from the Coromandel Coast, when they reach 18 months of age. A liquid extract is obtained through a proprietary hydro-extraction process; the extract is snap-frozen and freeze-dried, producing the highest quality bioactive compound, GlycoMarine™(Biolane).
As shown by clinical research, not only is GlycoMarine™(Biolane) a safe and effective anti-inflammatory, it protects the stomach from potentially harmful effects of non-steroidal anti-inflammatory drugs (NSAIDs). This gastro-protective effect is particularly relevant as many arthritis sufferers take NSAIDs along with GlycoMarine™(Biolane).
In addition to the anti-inflammatory and gastro-protective actions of GlycoMarine™(Biolane), it has been shown to be “chondroprotective” thus protecting the joints from deterioration and assisting in the healing process.

Dr. Henry ChengHenry Cheng Answers questions on your health issues.

Q. Why does the new generation of the New Zealand Green Lipped Mussel work so well for arthritis?
A. Maori Miracle is the new generation of New Zealand Green Lipped Mussel (Perna Canaliculus) supplement. In addition to glucosamine this mussel extract has 8 other glycosaminoglycans that are further reinforced with Collagen Type II from chicken cartilage. It also contains a fatty acid ester (Cetyl-Myristoleate) that doubles up as an immune modulator, and a herbal pain killer salicin from White Willow Bark. It has anti-inflammatory actions and lubricates the joint by improving the synovial fluid. It is suitable for both osteoarthritis and rheumatoid arthritis.

Dr. Henry Cheng: medical graduate of the University of London, England; Bachelor of Medicine( M.B.); Bachelor of Surgery (B.S.); Post-graduate Degree in Diagnostic Radiology (D.M.R.D.); 2 year course in complementary medicine with Canadian College of Naturopathic Medicine; Certified Natural Products Advisor (C.N.P.A.); practiced family medicine & radiology for 12 years; trained in orthodox/western medicine and herbal/homeopathic medicine